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ROXICODONE (oxycodone hydrochloride) ® may trigger spasm on the sphincter of Oddi and should be utilized with caution in patients with biliary tract condition, such as acute pancreatitis. Opioids like ROXICODONE (oxycodone hydrochloride) ® may trigger raises while in the serum amylase degree.Before taking oxycodone, tell your medical professional